Ricerca

Progetti di ricerca

"Visuo-motor assessment in Parkinson's disease: a multimodal study"

Responsabile: dott. Antimo Buonocore
Data inizio: 2023
Data fine: 2025

Among neurodegenerative disorders, Parkinson's disease (PD) increasingly burdens individuals and poses challenges for healthcare systems, spurring the development of new tools and technologies for early diagnosis and treatment. This project proposes using eye-tracking technologies as a low-cost, non-invasive method to test oculomotor inhibition as potential biomarkers for PD. Additionally, the simultaneous acquisition of brain activity through functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) will elucidate the structural and functional changes in brain activity associated with PD's progression, observed in a series of test-retest paradigm studies at 6 and 12 months. Lastly, the project includes a clinical intervention protocol that employs transcranial magnetic stimulation on brain areas linked to dysfunctional oculomotor behavior, aiming to modify visuomotor deficits in PD patients. The project's outcome is expected to enhance the overall understanding of PD, providing a deeper pathological characterization and, crucially, offering much-needed clinical tools and intervention methods to assist clinicians in making accurate PD diagnoses and prognoses.